Evaluation of a Novel Ocular Lubricating Eye Drop

The objective of this 2-part study is to assess the safety and tolerability of the new ocular lubricating drop ABR2 during short-term use in subjects for the temporary relief of ocular discomfort due to dryness of the eye. In Part 1, participant will receive 1 drop of ABR2 in one eye and through assessments over a 1-hour period. In Part 2, participant will use 1 drop of ABR2 at least two times a day for 28-day period (may use up to 4 times a day as needed) This is a single arm, open label study with no placebo or comparative arm.

NCT Number	NCT07593404
Lead Sponsor	Pleryon Therapeutics (Hangzhou) Limited Collaborators: University of Waterloo
Conditions	Dry Eye Syndrome (DES)
Enrollment	40 participants
Start Date	2026-05
Primary Completion	2027-01 (estimated)
Study Completion	2027-05 (estimated)
Updated on ClinicalTrials.gov	2026-05-19