Clinical Trial

Clinical Evaluation of the Access Socket Flexible Socket for Transtibial Prosthesis

Study acronym: AS-TT
Recruiting
View on ClinicalTrials.gov →
Summary
Transtibial amputation significantly impacts patient autonomy and quality of life, primarily due to the limitations of conventional rigid sockets, which restrict comfort and joint range of motion. The Access Socket (AS) is an innovative prosthetic socket combining a rigid carbon-fiber structure in key load-bearing areas with flexible urethane-resin (ProtheFLEX®) zones in regions typically rigid in conventional sockets. This hybrid design aims to improve comfort and pressure distribution while preserving the mechanical properties required for ambulation. The AS has already demonstrated benefits in transfemoral amputees and is now reimbursed in France for that population. A preliminary uncontrolled study in 12 transtibial amputees suggested significant improvements in perceived function, comfort, satisfaction, and mobility. This multicenter, randomized, open-label, two-arm crossover study aims to compare the (AS) with the standard rigid socket (RS) in 25 adults with transtibial amputation. Participants will wear each socket for approximately 4 weeks (after a 1-2 week adaptation period) in a randomized order. The primary outcome is the Patient Specific Functional Scale (PSFS). Secondary outcomes include comfort (SCS), satisfaction (OPUS), psychosocial adjustment (TAPES-R), mobility (PLUS-M), prosthesis utility (PEQ-U), and the proportion of patients electing to keep the AS at study completion.
Trial Details
NCT Number NCT07592325
Lead Sponsor Union de Gestion des Etablissements des Caisses d'Assurance Maladie - Nord Est
Collaborators: Institution Nationale des Invalides, Hôpital Filieris de Freyming-Merlebach, Ortho Access, H20 Orthopedie, Otto Bock France SNC, Hôpital d'Instruction des armées Percy, Clinical Investigation Center - University Hospital Grenoble
Conditions Transtibial Amputation, Lower Limb Amputation Below Knee
Enrollment 25 participants
Start Date 2026-04-27
Primary Completion 2027-04-27 (estimated)
Study Completion 2027-10-30 (estimated)
Updated on ClinicalTrials.gov 2026-05-18