Clinical Trial

Evaluation of Slit-like Adjusted Mathieu Versus Onlay Island Flap for Hypospadias Repair in Pediatrics

Completed
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Summary
* Purpose\*\* To compare the Slit-like Adjusted Mathieu (SLAM) technique versus the inner transverse preputial onlay island flap for repair of anterior and mid-penile hypospadias with narrow urethral plate, evaluating complication rates, surgical outcomes, and cosmetic results. * Methods\*\* This prospective randomized controlled study included 80 patients with anterior and mid-penile hypospadias with a urethral plate \<6 mm, conducted at Al-Azhar University Hospitals, Cairo, Egypt, from May 2020 to October 2025. Patients were randomly allocated to SLAM repair (Group A, n=40) or inner transverse preputial onlay island flap (Group B, n=40). Follow-up ranged from 24 to 48 months. Outcomes were assessed using the Hypospadias Objective Scoring Evaluation (HOSE) questionnaire.
Trial Details
NCT Number NCT07592026
Lead Sponsor Al-Azhar University
Conditions Narrow Urethral Plate Hypospadias
Enrollment 80 participants
Start Date 2020-05-01
Primary Completion 2025-10-31 (estimated)
Study Completion 2025-10-31 (estimated)
Updated on ClinicalTrials.gov 2026-05-18