Clinical Trial

Effect of Ancestry Supplementation in Subjects With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

Study acronym: Ancestry
Enrolling by Invitation
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Summary
The goal of this clinical trial is to evaluate the effect of Ancestry, a supplement made from Mexican-origin foods (nopal, cacao, and cricket) in adults with Metabolic dysfunction-associated steatotic liver disease (MASLD). The main questions it aims to answer are: * Does the supplementation with Ancestry improve the hepatic steatosis grade in participants with MASLD? * Does the supplementation improve biochemical and anthropometric parameters in participants with MASLD? * Does the supplementation enrich the abundance of beneficial bacteria in the gut microbiota of participants? Researchers will compare the supplement group to a placebo group to see if the supplement is effective. Participants will: * Take the supplement or a placebo every day for 3 months. * Receive nutritional guidance from a trained dietitian to control dietary intake. * Attend follow-up clinic visits every month for monitoring and checkups.
Trial Details
NCT Number NCT07592013
Lead Sponsor University of Guadalajara
Collaborators: Instituto de Salud Digestiva y Hepatica S.A de C.V., Instituto Tecnologico y de Estudios Superiores de Monterey
Conditions MASLD
Enrollment 60 participants
Start Date 2025-02-26
Primary Completion 2026-10 (estimated)
Study Completion 2027-02 (estimated)
Updated on ClinicalTrials.gov 2026-05-18