Spatiotemporal Evolution of Traditional Chinese Medicine Mechanisms in Acute Ischemic Stroke Treated With Dengzhan Xixin and Dengzhan Shengmai

To integrate large-scale RCT data on clinical symptoms, TCM syndromes, prognosis, and multi-omics profiles, construct a spatiotemporal dynamic network for disease-syndrome evolution of acute ischemic stroke (AIS) in the acute and recovery phases, evaluate the efficacy and safety of sequential treatment with Erigeron breviscapus-Dengzhan Shengmai for AIS, and provide evidence for precise syndrome differentiation and individualized therapy.Secondary Objective:To investigate the optimal time window and key intervention targets of sequential treatment with Erigeron breviscapus-Dengzhan Shengmai for AIS.

NCT Number	NCT07591883
Lead Sponsor	Guangdong Provincial Hospital of Traditional Chinese Medicine Collaborators: Nanfang Hospital, Southern Medical University
Conditions	Ischemic Strokes, Traditional Chinese Medicine (TCM), Prognosis
Enrollment	358 participants
Start Date	2026-06-01
Primary Completion	2029-07-30 (estimated)
Study Completion	2029-07-31 (estimated)
Updated on ClinicalTrials.gov	2026-05-18