Physical Activity Level at Home in CMT1A Patients: Wearable Sensor Assessment

Charcot-Marie-Tooth disease type 1A (CMT1A) is the most common hereditary peripheral neuropathy, affecting approximately 26,000 patients in France. It presents as chronic and progressive sensorimotor deficits predominantly affecting the distal lower limbs, with onset typically in childhood. There is currently no specific pharmacological treatment; management remains symptomatic. This research will: In the long run, validated wearable sensors could improve patient follow-up, personalize rehabilitation, and support the design of clinical trials for CMT1A - including trials of the novel "Nano-Cur" treatment currently under development.

NCT Number	NCT07591779
Lead Sponsor	University Hospital, Limoges Collaborators: Limoges University
Conditions	Charcot-Marie-Tooth Disease, Type IA, Peripheral Neuropathy Hereditary, Motor Activity, Walking, Difficulty, Neuromuscular Diseases
Enrollment	60 participants
Start Date	2026-06-01
Primary Completion	2027-04-15 (estimated)
Study Completion	2027-06-30 (estimated)
Updated on ClinicalTrials.gov	2026-05-22