Clinical Trial

Titanium-prepared Platelet-rich Fibrin for Treatment of Gingival Recession Using the VISTA Technique

Completed
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Summary
This split-mouth randomized clinical trial aims to compare the effectiveness of titanium-prepared platelet-rich fibrin (T-PRF) and connective tissue graft (CTG) in the treatment of Miller Class I and II gingival recession using the Vertical Incision Subperiosteal Tunnel Access (VISTA) technique. Twenty systemically healthy adult participants with bilateral gingival recession defects will receive both interventions, with one side randomly assigned to T-PRF and the contralateral side assigned to CTG. Clinical outcomes including recession depth, attached gingival width, probing depth, relative attachment level, healing, and patient satisfaction will be evaluated over a 6-month follow-up period.
Trial Details
NCT Number NCT07591142
Lead Sponsor Arab International University
Collaborators: Damascus University
Conditions Gingival Diseases, Gingival Recession
Enrollment 20 participants
Start Date 2025-08-12
Primary Completion 2026-01-12 (estimated)
Study Completion 2026-04-25 (estimated)
Updated on ClinicalTrials.gov 2026-05-15