D-RSBI Versus RSBI for Predicting Weaning Success in COPD Patients

This prospective observational cohort study aims to compare the predictive accuracy of diaphragmatic rapid shallow breathing index (D-RSBI) versus traditional rapid shallow breathing index (RSBI) for predicting weaning success from invasive mechanical ventilation in COPD patients. Diaphragmatic ultrasound measurements will be performed during spontaneous breathing trials, and patients will be followed for 72 hours after extubation to assess weaning outcomes.

NCT Number	NCT07590362
Lead Sponsor	Sohag University
Conditions	Chronic Obstructive Pulmonary Disease (COPD), Mechanical Ventilator Weaning
Enrollment	100 participants
Start Date	2026-04-15
Primary Completion	2027-05 (estimated)
Study Completion	2027-06 (estimated)
Updated on ClinicalTrials.gov	2026-05-15