Clinical Trial

Research on the Efficacy and Safety of Targeted Suprachiasmatic Nucleus Electrical Stimulation for Improving Metabolic Disorders in Patients With Stable Bipolar Disorder Comorbid With Obesity

Recruiting
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Summary
This study aims to stabilize the patients with bipolar disorder (BD) comorbid with obesity in the stable phase by using temporal interference stimulation (TIS ) intervention. It intends to investigate the changes in key metabolic molecules such as GLP-1 circadian rhythm, and further explore the molecular mechanism of their metabolic disorders.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2026-05-11.
Trial Details
NCT Number NCT07589647
Lead Sponsor First Affiliated Hospital of Zhejiang University
Conditions Bipolar Disorder (BD)
Enrollment 70 participants
Start Date 2026-04-27
Primary Completion 2026-12-31 (estimated)
Study Completion 2027-03-31 (estimated)
Updated on ClinicalTrials.gov 2026-05-27