Intertransverse Process Block Versus M-TAPA Block After Laparoscopic Cholecystectomy

This randomized clinical trial aims to evaluate and compare the analgesic efficacy of the Intertransverse Process Block (ITPB) and the Modified Thoracoabdominal Nerve Block through Perichondrial Approach (M-TAPA) in patients undergoing laparoscopic cholecystectomy. The primary outcome is the Visual Analog Scale (VAS) score within the first 24 hours after surgery. Secondary outcomes include total opioid consumption, requirement for rescue analgesia, block- related complications and adverse effects (hematoma, pneumothorax, local anesthetic systemic complications, vascular puncture, and infection), patient satisfaction assessed using a Likert scale, quality of recovery assessed using the QoR-15 questionnaire, and incidence of postoperative nausea and vomiting.

NCT Number	NCT07589491
Lead Sponsor	Antalya City Hospital
Conditions	Intertransverse Process Block, Mtapa Block, Laparoscopic Cholecystectomy, Postoperative Pain, Regional Anaesthesia
Enrollment	60 participants
Start Date	2026-11-15
Primary Completion	2027-09-30 (estimated)
Study Completion	2027-10-30 (estimated)
Updated on ClinicalTrials.gov	2026-06-16