Clinical Trial

Genicular Nerve Versus Adductor Canal Block for Postoperative Analgesia

Active, Not Recruiting
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Summary
Severe postoperative pain following total knee arthroplasty (TKA ) has been shown to negatively affect early mobilization, physical rehabilitation, time to discharge, and overall post-operative recovery.Therefore, reducing postoperative pain and early mobilization has become critical in reducing early mortality, preventing future chronic pain, and limiting the use of opioids The adductor canal block (ACB) has been found to be an excellent alternative to the FNB, providing adequate analgesia to the anterior knee compartment while enabling an improved postoperative range of motion by sparing motor branches to the quadriceps muscles . However, patients do not achieve adequate posterior knee analgesia as ACB pain relief is primarily limited to the anterior capsule of the knee. Genicular nerve block (GNB) and radiofrequency ablation of genicular nerves (RFGN) were originally introduced by Choi et al. as a therapeutic alternative for chronic knee OA and were quickly adopted for use in patients undergoing TKA due to the significant pain reduction and functional improvement observed in these patients . GNBs target five main innervating branches of the knee, including the superomedial, inferomedial, superolateral, inferolateral genicular nerves, and the infrapatellar branch of the saphenous nerve.
Trial Details
NCT Number NCT07588958
Lead Sponsor Zagazig University
Conditions Postoperative Pain After Total Knee Arthroplasty
Enrollment 42 participants
Start Date 2023-10-01
Primary Completion 2026-05-06 (estimated)
Study Completion 2026-06-19 (estimated)
Updated on ClinicalTrials.gov 2026-05-15