Pain Assessment During Rapid Sequence Induction

Rapid sequence induction (RSI) is a standard anesthesia technique used in patients at risk of aspiration. Although tracheal intubation following RSI is a frequent and painful procedure, no study has yet evaluated nociception using the Analgesia Nociception Index (ANI) during this procedure. This monocentric prospective observational study aims to describe the impact of RSI on pain measured by ANI, and to explore early complications (desaturation, hypotension, regurgitation) and factors associated with pain and complications. 150 patients undergoing RSI in the visceral surgery operating room at CHPG Monaco will be analyzed.

NCT Number	NCT07588165
Lead Sponsor	Centre Hospitalier Princesse Grace
Conditions	Rapide Sequence Induction, Tracheal Intubation, Nociception, General Anesthesia
Enrollment	150 participants
Start Date	2026-05-21
Primary Completion	2028-05 (estimated)
Study Completion	2028-05 (estimated)
Updated on ClinicalTrials.gov	2026-05-27