Convective Radio-frequency Water Vapor Energy Verses Trans-urethral Enucleation of Prostate for Management of Benign Prostatic Hyperplasia

Convective RF water vapor energy was introduced as a minimally invasive, radio-frequency thermal energy-based treatment, designed to convectively deliver sterile water vapor, or steam for targeted ablation limited to the transition and central zones in men with clinical BPH. Thus. the aim of the study is to compare Convective RF water vapor energy (Rezum) with trans-urethral enucleation of the prostate (TUEP) regarding efficacy in terms of lower urinary tract symptoms (LUTS) improvement, international prostatic symptoms score (IPSS), improving of the maximum flow rate (Qmax), worsening of erectile and ejaculatory function, and safety regarding post operative complications \& hospital stay.

NCT Number	NCT07587333
Lead Sponsor	Beni-Suef University
Conditions	BPH (Benign Prostatic Hyperplasia)
Enrollment	70 participants
Start Date	2025-03-01
Primary Completion	2026-03-01 (estimated)
Study Completion	2026-05-01 (estimated)
Updated on ClinicalTrials.gov	2026-05-19