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Multimodal Fascial Plane Block for Postoperative Analgesia in Isolated CABG Surgery

Study acronym: BLOCKCABG
StatusCompleted
PhaseNot applicable
Started
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Record History

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  1. Notable Start date: Jan 1, 2026 to Feb 15, 2026
    • Trial completed
    • Final enrollment: 88 participants (planned 56)
  2. Minor Trial status: Recruiting to Completed Show 6 more changesShow less
    • Enrollment target: estimated 56 to confirmed 88
    • Primary completion date changed from estimate of Aug 2026 to Aug 30, 2026
    • Study completion date changed from estimate of Sep 2026 to Sep 15, 2026
    • Eligibility criteria expanded, about 12 words
    • Site details revised
    • Publications: details revised at 3 of 3 entries
  3. Minor Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Postoperative pain following coronary artery bypass grafting (CABG) via median sternotomy remains a significant clinical problem and is associated with increased opioid consumption and postoperative complications. Fascial plane blocks have emerged as part of multimodal analgesia strategies in cardiac surgery. This prospective, randomized, controlled, single-blinded study aims to evaluate the effect of an induction-time multimodal fascial plane block package-consisting of bilateral superficial parasternal block, bilateral serratus anterior plane block, and adductor canal block-on postoperative analgesia, opioid consumption, and clinical outcomes in patients undergoing elective isolated CABG with saphenous vein graft harvesting. Patients will be randomized in a 1:1 ratio to receive either the multimodal fascial plane block package in addition to standard postoperative analgesia or standard postoperative analgesia alone. The primary outcome is total opioid consumption within the first 24 postoperative hours. Secondary outcomes include pain scores, time to first opioid requirement, extubation time, postoperative pulmonary complications, atrial fibrillation, and length of ICU and hospital stay.
Trial Details
NCT Number NCT07587320
Lead Sponsor Saglik Bilimleri Universitesi
Conditions
(from sponsor)
Coronary Artery Bypass Graft (CABG), Postoperative Pain, Sternotomy
Related terms Postoperative Pain
Enrollment 88 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov