Clinical Trial

Pucotenlimab Plus Becotatug Vedotin in Perioperative Treatment of Locally Advanced Resectable Head and Neck Squamous Cell Carcinoma

Recruiting Phase 2
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Summary
A multicenter, randomized, double-blind, phase II clinical study designed to evaluate the safety, pharmacokinetics, and preliminary efficacy of Becotatug Vedotin for Injection in combination with PD-1 in patients with locally advanced resectable head and neck squamous cell carcinoma
Protocol Amendment History 1 change
critical Recruitment opened 2026-07-10
Trial Details
NCT Number NCT07586124
Lead Sponsor Lepu Biopharma Co., Ltd.
Conditions Head and Neck Squamous Cell Carcinoma
Enrollment 80 participants
Start Date 2026-07-06
Primary Completion 2027-12 (estimated)
Study Completion 2028-12 (estimated)
Updated on ClinicalTrials.gov 2026-07-09