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Study of the Effects of Acute Exposure to Moderate Altitude Hypoxia on Prospective Memory.

Study acronym: HYPRO
StatusNot Yet Recruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗

Record History

  1. Minor Study First Submitted
The goal of this study is to investigate whether prospective memory, i.e., memory for delayed intentions, is impaired at moderate altitude (4,000m). It will also allow to study the effect of air and oxygen administration during hypoxia exposure. The main questions it aims to answer are: * Does moderate acute hypoxia impair prospective memory ? * If so, does air or oxygen adminsitration induce a restoration of prospective memory? Researchers will compare cognitive performance during normobaric hypoxia exposure to cognitive performance during normoxia (control situation). Participants will: * Session S0. Perform a battery of neuropsychological tests and questionnaires). EEG will be recorded during tests. A cheek swab will be performed. * Sessions S1 and S2. Perform several cognitive tasks while exposed to hypoxia and to normoxia (2 different sessions, randomized order) in a normobaric chamber. These are standardized cognitive tests administered on a computer and cognitive tests embedded in a flight simulator scenario. Various questionnaires will be performed on a regular basis. Several physiological measurements will be performed continuously: EEG, ECG, SpO2 and breathing rate. Blood pressure will be measured at the beginning and at the end of hypoxia/normoxia exposure. A blood sample will also be performed. At last, participants will inhale air or oxygen through a mask while making a cognitive task in the chamber.
Trial Details
NCT Number NCT07585227
Lead Sponsor Direction Centrale du Service de Santé des Armées
Conditions
(from sponsor)
Hypoxia, Hypoxia Brain, Hypoxia Altitude Simulation Test, Hypoxia in Healthy Individuals, Hypoxia, Altitude, Hypoxia, Brain, Altitude, Altitude Hypoxia +1 more
Related terms Altitude Sickness, Hypoxia, Hypoxia, Brain
Enrollment 50 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov