Evaluation of Fluid Biomarkers Around Implants Exhibiting Early Stage Periimplant Bone Loss

This study aimed to compare biological mediators known to be important in peri-implant diseases in implants with and without early stage marginal bone loss. A total of 118 implants in 59 patients were designated as test and control groups. The radiographic and periodontal data of the included implants, along with peri-implant sulcus fluid samples, were evaluated.

NCT Number	NCT07584759
Lead Sponsor	Pamukkale University Collaborators: Pamukkale University scientific research project department
Conditions	Peri-implant Bone Loss, Peri-implant Marginal Bone Loss, Marginal Bone Loss, Peri-Implant Health
Enrollment	59 participants
Start Date	2025-03-06
Primary Completion	2025-09-06 (estimated)
Study Completion	2025-09-06 (estimated)
Updated on ClinicalTrials.gov	2026-05-13