Investigation of Motorized Lower-limb Prostheses

The goal of this clinical trial is to learn if a motorized prosthesis can improve mobility in individuals with amputation. The main question it aims to answer is: * Does motorized prosthesis improve ambulation speed, balance, control, or efficiency when performing everyday activities? * What problems arise when using a motorized prosthesis? Researchers will compare mobility of the participants when using and not using the motorized prosthesis to see if mobility and/or function improves. Participants will perform various activities with and without the motorized prosthesis including: * Walking at a mild incline/decline (0°-15°) on treadmill or over-ground * Ascending or descending stairs * Stand to sit and sit to stand transitions * All terrain walking over ground * Turning * Any combination of the above-mentioned activities

NCT Number	NCT07584707
Lead Sponsor	Northern Arizona University
Conditions	Ambulation With the "Take Home" or Passive Prosthesis, Ambulation With the Motorized Prosthesis in the "Off" Configuration, Ambulation With the Motorized Prosthesis in the "Transparent" Condition, Ambulation With the Motorized Prosthesis in the "Powered" Condition
Enrollment	20 participants
Start Date	2026-04-16
Primary Completion	2029-03-15 (estimated)
Study Completion	2029-03-15 (estimated)
Updated on ClinicalTrials.gov	2026-05-13