Pharmacokinetics of Kava and Kratom Alone and in Combination

This study is being conducted to evaluate how different formulations of the Feel Free® Tonic containing Kava, Kratom, or a combination of both are processed in the body in healthy adults. The goal is to compare the pharmacokinetic profiles and safety of the combined herbal formulation with Kava alone and Kratom alone to better understand how these ingredients behave when taken individually versus together.

NCT Number	NCT07583407
Lead Sponsor	Botanic Tonics, LLC Collaborators: Nutrasource Pharmaceutical and Nutraceutical Services, Inc.
Conditions	Herb-Herb Interaction, Pharmacokinetics
Enrollment	18 participants
Start Date	2026-05-04
Primary Completion	2026-09-04 (estimated)
Study Completion	2026-09-04 (estimated)
Updated on ClinicalTrials.gov	2026-05-13