Perioperative Prospective Follow Up Of Cannabis Consumers and Discrepancy Use

This study includes a prospective non interventional study that aims to asses the prevalence of cannabis use among patients undergoing elective surgery and evaluates its impact on perioperative outcomes, including pain, opioid consumption, nausea, anxiety, and sleep disturbances. A matched control cohort will provide comparative data. Discrepancies between self-reported and objectively measured cannabis use will be assessed using blood samples and urine samples. Participants will be requested to complete preoperative and postoperative questionnaires on days 1, 2, 3, 7, and 30 to monitor cannabis use and perioperative symptoms. This study aims to clarify the perioperative effects of cannabis use and the accuracy of patient-reported consumption.

NCT Number	NCT07582445
Lead Sponsor	Hadassah Medical Organization
Conditions	Cannabinoid, Discrepancy With Clinical Examination
Enrollment	600 participants
Start Date	2026-05-06
Primary Completion	2026-07-10 (estimated)
Study Completion	2027-12-10 (estimated)
Updated on ClinicalTrials.gov	2026-05-12