Clinical Trial

Eccentric Exercise, Muscle Damage, and Oxygen Uptake Across Menstrual Cycle Phases

Study acronym: EEMDO-MC
Completed
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Summary
The existing literature examining the effect of female sex hormones across the phases of the menstrual cycle on muscle microdamage and oxygen uptake is limited. The protective role of estrogens against muscle microdamage is supported by findings from some studies; however, it is questioned by others. The aim of the present study was to investigate the effect of eccentric exercise on biomarkers of muscle microdamage and on oxygen uptake during two phases of the menstrual cycle in healthy premenopausal women.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2026-05-06.
Trial Details
NCT Number NCT07581067
Lead Sponsor National and Kapodistrian University of Athens
Conditions Menstrual Cycle, Exercise Performance Impairment
Enrollment 12 participants
Start Date 2025-05-15
Primary Completion 2025-08-05 (estimated)
Study Completion 2026-01-22 (estimated)
Updated on ClinicalTrials.gov 2026-05-15