Studying Heart Ablation After Left Atrial Closure in High-Bleeding-Risk Atrial Fibrillation Patients

The purpose of this multicenter study is to collect information from routine clinical practices for patients with left atrial appendage occlusion (LAAO) devices presenting for pulmonary vein isolation (PVI) or left atrial ablation. Assessment will include characterization of patient characteristics, procedural details, management of post-procedure anticoagulation, and clinical outcomes.

NCT Number	NCT07580937
Lead Sponsor	University of Chicago Collaborators: Rush University
Conditions	Atrial Fibrillation, Atrial Arrhythmia
Enrollment	198 participants
Start Date	2022-03-08
Primary Completion	2024-12-10 (estimated)
Study Completion	2026-03-30 (estimated)
Updated on ClinicalTrials.gov	2026-05-12