Effects of Supplementation on Performance in Football Players

This study investigated the effects of short-term supplementation with taurine, caffeine, and phosphatidylserine on physical and cognitive performance in professional male football players. Eighty-one players were randomly assigned to one of three groups: placebo, taurine plus caffeine, or taurine plus caffeine combined with phosphatidylserine. Supplementation was administered for 10 days, with a final dose taken 60 minutes before a standardized 105-minute football training session. Primary and secondary outcomes included sprint performance, reaction time, GPS-derived locomotor variables, and technical and tactical performance indicators. The aim of the study was to evaluate whether combined multi-ingredient supplementation could improve performance and attenuate fatigue-related declines under match-like conditions.

NCT Number	NCT07580248
Lead Sponsor	Krzysztof Mizera
Conditions	Physical Performance, Cognitive Performance
Enrollment	81 participants
Start Date	2025-03-25
Primary Completion	2025-04-05 (estimated)
Study Completion	2025-04-05 (estimated)
Updated on ClinicalTrials.gov	2026-05-26