PRP Improves Blastocyst Formation in ICSI Cycles

The goal of this clinical trial is to learn if platelet rich plasma (PRP) works to improve embryo development rates and embryo quality in IVF cycles, involving male adult patients with severe sperm disorders. The main questions it aims to answer are: * Does PRP improve sperm quality of male adult patients undergoing IVF? * Does PRP improve embryo development and embryo quality of the IVF patients? Researchers will compare embryos from IVF patients treated with PRP to those not treated with PRP to see if PRP improves embryo development and embryo quality. Participants will: * Provide semen sample for IVF * Provide blood sample for PRP preparation * Have PRP obtained from their blood added to their sperm sample

NCT Number	NCT07579858
Lead Sponsor	Stella Maris Women and Children Hospital Collaborators: Halim Fertility Center
Conditions	Severe Oligoasthenoteratozoospermia, Sperm Quality, Spermatazoa Disorders, Sperm Parameters in Fertile and Infertile Men, Embryo Development, Embryo Quality, Embryologic Parameters, Platelet Rich Plasma +5 more
Enrollment	66 participants
Start Date	2023-01-01
Primary Completion	2023-08-30 (estimated)
Study Completion	2023-12-30 (estimated)
Updated on ClinicalTrials.gov	2026-05-12