Clinical Trial

Impact of Iridotomy/Iridectomy Size on Postoperative Pupillary Block and Dysphotopsia Following DMEK

Not Yet Recruiting
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Summary
Descemet membrane endothelial keratoplasty (DMEK) is the standard surgical treatment for corneal endothelial disorders. A postoperative pupillary block may occur despite routine preoperative laser iridotomy or intraoperative surgical iridectomy. Insufficient size or incomplete patency of the iridotomy/iridectomy (IT) may contribute to this complication, while excessively large openings may be associated with postoperative dysphotopsia. This prospective observational study investigates the association between IT size measured by anterior segment optical coherence tomography (AS-OCT) and the occurrence of postoperative pupillary block and dysphotopsia after DMEK.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2026-05-04.
Trial Details
NCT Number NCT07577635
Lead Sponsor University of Leipzig
Conditions Pupillary Block After DMEK, Laser Iridotomy / Surgical Iridectomy, Dysphotopsia, Descemet Membrane Endothelial Keratoplasty (DMEK)
Enrollment 100 participants
Start Date 2026-06-01
Primary Completion 2027-01-01 (estimated)
Study Completion 2027-07-01 (estimated)
Updated on ClinicalTrials.gov 2026-07-02