Calming Minds Study

The goal of this study is to understand why certain treatments help people reduce repetitive negative thinking (RNT), which is common in many mental health problems. We want to: 1. Figure out what actually causes repetitive negative thinking to decrease when people use cognitive-behavioral therapy (CBT). 2. Find out which parts of RNT-focused CBT are the most important - the parts that truly make a difference in reducing RNT. The main result we will look at is how much a person's repetitive negative thought patterns change from the start of the study to the end of treatment (16 weeks). We will measure this using the Perseverative Thinking Questionnaire at baseline and week 16.

NCT Number	NCT07577401
Lead Sponsor	University of California, Los Angeles Collaborators: University of Exeter
Conditions	Anxiety, Anxiety Depression, Worry, Depression, Rumination - Thoughts
Enrollment	500 participants
Start Date	2026-06-08
Primary Completion	2028-06-14 (estimated)
Study Completion	2028-06-14 (estimated)
Updated on ClinicalTrials.gov	2026-05-11