This record was last updated June 15, 2026 (before its estimated June 26, 2026 completion). Its status may not reflect the trial's current state.
Summary
The purpose of this study is to learn if a medicine called itraconazole changes how the body processes the study medicine (PF-08642534) in healthy adults.
This study is seeking healthy participants (men or women) who:
* are aged 18 to 65 years of age
* are confirmed to be healthy by their medical history and medical tests
* have body mass index (BMI) of 16 to 30 kilograms per meter squared
* have a total body weight of more than 50 kilograms.
Participants will receive single doses of the study medicine (PF-08642534) with and without itraconazole.
The total planned time of participation is about 12 weeks. The study consists of:
* a screening period of up to 28 days before taking study drug
* about 4 weeks of staying in the study clinic
* a follow-up contact that will occur 28 to 35 days after taking itraconazole the last time.
Protocol Amendment History
1 change
criticalTrial status changed: Not Yet Recruiting → Active, Not Recruiting2026-06-16