Allogeneic Dental Pulp Stem Cells for the Treatment of Periodontitis

The overall objective of this study is to evaluate the safety and efficacy of allogeneic human dental pulp stem cells (DPSCs) injected for the treatment of chronic periodontitis in humans. It aims to develop a stem cell injection therapy that promotes the regeneration of periodontal soft and hard tissues through a non-invasive (minimally invasive) procedure, thereby replacing traditional traumatic periodontal surgery.

NCT Number	NCT07574840
Lead Sponsor	The First Affiliated Hospital of Xinxiang Medical College
Conditions	Periodontitis
Enrollment	30 participants
Start Date	2026-04-15
Primary Completion	2027-12-31 (estimated)
Study Completion	2028-12-31 (estimated)
Updated on ClinicalTrials.gov	2026-05-08