Clinical Trial

Ultrasound Prediction of Esophageal Variceal Bleeding Risk

Not Yet Recruiting
View on ClinicalTrials.gov →
Summary
This prospective observational study aims to evaluate the accuracy of using routine abdominal ultrasound to predict the risk of esophageal variceal bleeding in adult patients with liver cirrhosis. Esophageal variceal bleeding is a serious complication of chronic liver disease. While upper gastrointestinal endoscopy is the current standard for diagnosing and grading these varices, it is an invasive procedure. In this study, researchers will use ultrasound to measure the patient's spleen size and portal vein diameter. These non-invasive measurements will then be compared to the results of a standard upper endoscopy performed within 48 to 72 hours. The goal is to determine if these simple ultrasound measurements can reliably predict the presence, grade, and bleeding risk of esophageal varices, which could potentially reduce the need for routine invasive endoscopic screenings in the future.
Trial Details
NCT Number NCT07571876
Lead Sponsor Assiut University
Conditions Variceal Bleeding, Ultrasonography, Esophageal Bleeding, Esophageal Varices, Liver Cirrhosis, Portal Hypertension, Chronic Liver Disease (CLD)
Enrollment 165 participants
Start Date 2026-04
Primary Completion 2027-04 (estimated)
Study Completion 2027-05 (estimated)
Updated on ClinicalTrials.gov 2026-05-06