Clinical Trial

Transcranial Magnetic Stimulation as a Treatment for Postpartum Obsessive Compulsive Disorder

Study acronym: Project MOM
Not Yet Recruiting
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Summary
The goal of this clinical trial is to learn if accelerated transcranial magnetic stimulation (TMS) is a feasible treatment for obsessive compulsive disorder that worsens or starts within 12 months of childbirth. The main questions it aims to answer are: Is TMS a tolerable and acceptable treatment for postpartum women with OCD? Does TMS improve OCD symptoms in postpartum women? Does TMS change connectivity between areas of the brain involved in OCD? Participants will: 1. Receive 50 sessions of a type of TMS called continuous theta burst stimulation (cTBS) over the course of two weeks. 2. Complete clinical assessments before and after TMS, as well as at 1 and 3 months post-treatment 3. Undergo functional magnetic resonance imaging (fMRI) of the brain before and after TMS
Trial Details
NCT Number NCT07571187
Lead Sponsor Butler Hospital
Conditions Postpartum Obsessive Compulsive Disorder
Enrollment 15 participants
Start Date 2026-04
Primary Completion 2028-01 (estimated)
Study Completion 2028-06 (estimated)
Updated on ClinicalTrials.gov 2026-05-06