Clinical Trial

Neoadjuvant Tislelizumab + LM-302 + S-1 or Tislelizumab + SOX for CLDN18.2-Positive Gastric/GEJ Adenocarcinoma

Recruiting Phase 2
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Summary
In this study, the investigators will use Tislelizumab combined with LM-302 and S-1 versus Tislelizumab combined with SOX to treat Claudin 18.2-positive locally advanced gastric or gastroesophageal junction adenocarcinoma.
Trial Details
NCT Number NCT07569068
Lead Sponsor Ruijin Hospital
Conditions Gastric or Esophagogastric Junction Adenocarcinoma
Enrollment 88 participants
Start Date 2026-04-21
Primary Completion 2028-04-30 (estimated)
Study Completion 2029-04-30 (estimated)
Updated on ClinicalTrials.gov 2026-05-06