Clinical Trial

Effects of Non-Invasive Vagus Nerve Stimulation in Adolescent Burn Patients

Enrolling by Invitation
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Summary
This study will evaluate the effects of non-invasive vagus nerve stimulation in adolescents aged 12 to 18 years who have burn injuries. The study will include patients who have completed the acute phase after burn injury and who have symptoms such as anxiety, sleep problems, pain, or itching. Participants will be randomly assigned to one of two groups. One group will receive conventional physiotherapy together with non-invasive vagus nerve stimulation. The other group will receive only conventional physiotherapy. The treatment program will be applied 5 days per week for a total of 10 sessions. The study will assess whether non-invasive vagus nerve stimulation improves anxiety, sleep quality, pain, itching, and autonomic nervous system function. These outcomes will be measured before and after the treatment program using clinical scales and heart rate variability measurements.
Protocol Amendment History 1 change
critical Primary endpoint(s) modified 2026-05-08
Trial Details
NCT Number NCT07566923
Lead Sponsor Fenerbahce University
Conditions Burn Injury
Enrollment 60 participants
Start Date 2026-05-11
Primary Completion 2026-09 (estimated)
Study Completion 2026-09 (estimated)
Updated on ClinicalTrials.gov 2026-07-07