Clinical Trial

Holmium Laser Enucleation Of the Prostate Versus Water Vapor Therapy Of The Prostate on Sexual Function and Ejaculation

Completed
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Summary
This study aims to compare the effect of holmium laser enucleation of the prostate (HoLEP) versus water vapor therapy (Rezum) on sexual function and ejaculation in patients with benign prostatic hyperplasia (BPH). Benign prostatic hyperplasia is a common condition affecting aging men and may lead to lower urinary tract symptoms requiring surgical intervention. While both HoLEP and Rezum are effective minimally invasive treatments, their impact on sexual function, particularly ejaculation, remains an important concern. Participants will be assigned to undergo either HoLEP or Rezum therapy. Sexual function and ejaculatory outcomes will be evaluated using validated questionnaires before and after treatment. The study aims to determine which modality provides better preservation of sexual function while maintaining clinical efficacy.
Trial Details
NCT Number NCT07566689
Lead Sponsor Beni-Suef University
Conditions Benign Prostate Hypertrophy(BPH)
Enrollment 110 participants
Start Date 2024-04-03
Primary Completion 2025-12-03 (estimated)
Study Completion 2026-01-03 (estimated)
Updated on ClinicalTrials.gov 2026-05-05