This study aimed to investigate and compare the effects of low-intensity laser therapy, a photobiomodulation treatment, and proprioceptive neuromuscular facilitation on pain and disability in individuals with non-specific neck pain. This randomized controlled trial used the Numerical Pain Scale (primary outcome) and the Bournemouth Neck Pain Questionnaire to assess pain, a manual algometer to assess pain threshold, and the Neck Disability Index to assess disability. Three groups were included in this randomized controlled trial: Group 1: Photobiomodulation therapy (low-intensity laser therapy) + conventional physiotherapy; Group 2: Proprioceptive neuromuscular facilitation with stretching and strengthening + conventional physiotherapy; Group 3: Conventional physiotherapy only. We hypothesized that low-intensity laser therapy and proprioceptive neuromuscular facilitation would have distinct effects on pain and disability in chronic non-specific neck pain.