Clinical Trial

Adolescent Probiotics in Stressed Adolescents

Completed
View on ClinicalTrials.gov →
Summary
Stress is a normal human reaction to changes surrounding our reality, resulting in physical, emotional, and intellectual responses. Children and adolescents often experience high levels of stress. Age and gender may affect a child's ability to manage stress. Children and adolescents experiencing stress could be at an increased risk of poor cognitive, social, and emotional functioning. Probiotics are living microorganisms that could positively affect microbiota, support functions of numerous organs and systems, and overall human health. Most probiotics belong to the Lactobacillus genus. Probiotics can potentially support mental health, psychological function, and immune defenses. The purpose of this exploratory clinical trial is to investigate whether supplementation of the diets of adolescents experiencing moderate stress with the probiotic dietary supplement a blend of two probiotic Lactobacillus plantarum and one Lactobacillus brevis strains will support their emotions (e.g., psychological well-being, social relationship, stress levels, and self-efficacy), cognitive (e.g., attention, episodic and working memory) and immune functions (e.g., salivary IgA and salivary cytokine productions). This study is intended only to evaluate the dietary supplement's effect on the body's structure or function. Our investigation is not intended to mitigate, cure, treat, or prevent disease.
Trial Details
NCT Number NCT07565883
Lead Sponsor University of Utah
Collaborators: Kaneka Americas Holding Inc.
Conditions Cognitive Ability, General, Immune System Function, Emotions
Enrollment 104 participants
Start Date 2022-05-03
Primary Completion 2024-07-22 (estimated)
Study Completion 2024-11-25 (estimated)
Updated on ClinicalTrials.gov 2026-05-04