Effect of Modifying Magnesium Concentration in Citrate-enriched Dialysate on Serum Magnesium Levels

Individuals with ESKD and treated with hemodialysis have a high mortality risk. Associative studies suggest a relationship between serum magnesium concentration and mortality risk. The influence of magnesium concentration on mortality risk is unknown. This pilot study will explore whether altering dialysate magnesium concentration in the presence of citrate will change serum magnesium concentrations.

NCT Number	NCT07565779
Lead Sponsor	Universitaire Ziekenhuizen KU Leuven Collaborators: Fresenius AG
Conditions	Dialysis; Complications
Enrollment	54 participants
Start Date	2025-01-28
Primary Completion	2026-01-15 (estimated)
Study Completion	2026-01-31 (estimated)
Updated on ClinicalTrials.gov	2026-05-04