Clinical Trial

Effect of Benzydamine Hydrochloride Mouthrinse on Plaque Accumulation in Periodontally Healthy Female Subjects

Study acronym: BHCl-PLAQUE
Completed Phase 4
View on ClinicalTrials.gov →
Summary
The goal of this clinical trial is to evaluate the effect of a mouthrinse containing an active ingredient benzydamine hydrochloride in the absence of daily oral hygiene. The study includes periodontally healthy female subjects and experimental phase will last for three days. Plaque accumulation is the primary evaluated outcome, measured by a particular periodontal index called Plaque Control Record (PCR). Gingival inflammation (bleeding) is the secondary evaluated outcome, measured by a particular periodontal index called Bleeding on Probing (BoP). Researchers will compare benzyadamine hydrochloride mouthrinse to a placebo (a look-alike substance that contains no active ingredient) mouthwash to see whether benzydamine hydrochloride use results in greater plaque accumulation.
Trial Details
NCT Number NCT07565766
Lead Sponsor University of Zagreb
Conditions Plaque Induced Gingival Disease, Oral Health
Enrollment 50 participants
Start Date 2013-02
Primary Completion 2013-05 (estimated)
Study Completion 2013-05 (estimated)
Updated on ClinicalTrials.gov 2026-05-04