Clinical Trial

Examining Migration, Social Bonds, Transnationalism, and HIV Prevention Pathways Among African Immigrants.

Study acronym: MiST-Pathways
Not Yet Recruiting
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Summary
The goal of this mixed-methods pilot study is to learn whether migration experiences, social bonds, and transnational ties shape HIV prevention decision-making, including HIV testing, HIV self-testing (HIVST), and pre-exposure prophylaxis (PrEP) uptake, among first-generation African immigrants aged 18 to 50 residing in New York and Massachusetts. The main questions it aims to answer are: * What relationship typologies and migration-related relational mechanisms influence HIV testing, HIVST, and PrEP decision-making among African immigrants? * Can a relationship-tailored HIV prevention intervention component, co-developed with the community, demonstrate feasibility and acceptability among African immigrants? * Does exposure to the prioritized intervention component show directional increases in HIV testing intention, willingness to use HIVST, interest in PrEP, and readiness for relationship-based prevention communication? There is no comparison group. All Aim 3 participants receive the same co-developed intervention component. Participants will: * Complete a qualitative interview (60-90 minutes) and/or a structured electronic survey (15-20 minutes) about their relationship experiences, migration history, and HIV prevention behaviors. * Take part in a 3-4 hour structured group deliberation session called a Palava Hut Conversation to co-develop and prioritize HIV prevention intervention ideas. * Complete a baseline survey, receive the prioritized intervention component in a structured Zoom session, and complete a follow-up survey with an optional 60-90 minute cognitive interview for a subset of participants.
Protocol Amendment History 2 changes
notable Primary completion pushed: 2027-04 -> 2027-08 2026-06-30
minor Completion pushed: 2027-05 -> 2027-09 2026-06-30
Trial Details
NCT Number NCT07565584
Lead Sponsor State University of New York at Buffalo
Collaborators: Yale University
Conditions HIV Prevention, HIV Testing, Sexual and Reproductive Health
Enrollment 144 participants
Start Date 2026-08-04
Primary Completion 2027-08 (estimated)
Study Completion 2027-09 (estimated)
Updated on ClinicalTrials.gov 2026-06-29