Drug-Drug Interactions of JMKX003142 in Healthy Participants

This is a single-center, non-randomized, open-label, self-controlled, Phase I clinical trial to evaluate the drug-drug interactions (DDI) of JMKX003142 tablets in healthy adult participants. The study consists of five cohorts (Cohorts 1, 2, 3, 4, and 5). A total of 24 participants are planned enrollment in each of Cohorts 1, 2, 3, and 5, while 16 participants are planned for Cohort 4.

NCT Number	NCT07565441
Lead Sponsor	Jemincare Collaborators: Zhejiang Hangyu Pharmaceutical Co., Ltd.
Conditions	ADPKD (Autosomal Dominant Polycystic Kidney Disease)
Enrollment	112 participants
Start Date	2026-05-11
Primary Completion	2026-11-15 (estimated)
Study Completion	2027-02-28 (estimated)
Updated on ClinicalTrials.gov	2026-05-04