100-Year Human Aging Study

The 100-Year Human Aging Study is a prospective, pragmatic, observational trial enrolling participants across fixed and mobile clinical sites to undergo comprehensive multi-system health screening and longitudinal follow-up until death. Participants are followed to determine whether measurements taken at enrollment and repeated across the lifespan - individually and in combination - predict all-cause mortality, cause-specific mortality, incident serious disease, and functional disability. The study is designed to generate the surrogate endpoint validation data that longevity medicine currently lacks.

NCT Number	NCT07563777
Lead Sponsor	Longevity Metrics, Inc.
Conditions	Aging, Aging Well, All-Cause Mortality, Mortality, Metabolic Syndrome, Cardiovascular Diseases, Cognitive Dysfunction, Musculoskeletal Diseases +7 more
Enrollment	1,000,000 participants
Start Date	2025-02-09
Primary Completion	2099-12-31 (estimated)
Study Completion	2099-12-31 (estimated)
Updated on ClinicalTrials.gov	2026-06-11