JAK2 Expression in Androgenetic Alopecia Before and After Topical Minoxidil

Androgenetic alopecia is a common form of progressive hair loss. This prospective single-arm pre-post interventional study aims to assess tissue Janus Kinase 2 (JAK2) expression in patients with androgenetic alopecia by comparing balding and non-balding scalp at baseline, and to evaluate changes in JAK2 expression in balding scalp after 3 months of topical minoxidil 5% therapy. Clinical response will be assessed using standardized trichoscopic parameters.

NCT Number	NCT07563036
Lead Sponsor	Kasr El Aini Hospital
Conditions	Androgenetic Alopecia, Androgenic Alopecia
Enrollment	25 participants
Start Date	2026-02-01
Primary Completion	2026-10-01 (estimated)
Study Completion	2027-01-01 (estimated)
Updated on ClinicalTrials.gov	2026-05-01