SER-ABS-AUD: Bio-Psycho-Socio-Spiritual Predictors of AUD Recovery

Alcohol use disorder (AUD) remains a major public health burden in Romania, with very high alcohol-attributable mortality and years of life lost. Conventional treatment focuses on achieving abstinence, but the distinction between "struggle abstinence" (persistent cravings, anhedonia, white-knuckle willpower) and "serene abstinence" (anhedonia resolution, restored reward, meaning and quality of life) is poorly characterized in the Romanian context. This longitudinal observational study uses the Millon Clinical Multiaxial Inventory-IV (MCMI-IV) together with a brief neuropsychosocial-spiritual battery to identify which personality patterns and clinical syndromes predict serene versus struggle abstinence in adults with DSM-5 alcohol use disorder who maintain at least 12 months of sobriety in Romanian community recovery settings.

NCT Number	NCT07561749
Lead Sponsor	Grigore T. Popa University of Medicine and Pharmacy Collaborators: Association of Alcoholics in Recovery Clubs Don Orione
Conditions	Alcohol Abstinence
Enrollment	70 participants
Start Date	2026-04-20
Primary Completion	2026-09-01 (estimated)
Study Completion	2027-04-20 (estimated)
Updated on ClinicalTrials.gov	2026-05-07