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First-in Cancer-Type Phase I Study of FT536 for Recurrent WHO Grade 4 Astrocytoma

StatusRecruiting
PhasePhase 1
Started2026-04-23
View on ClinicalTrials.gov ↗
This is a single center, first-in cancer-type phase I clinical trial of FT536 for adult patients with recurrent WHO Grade 4 astrocytoma, irrespective of IDH-mutational status, for which a standard of care repeat craniotomy for gross tumor resection at time of first or second recurrence is achievable. Per this treatment schema, FT536 will be administered once intratumorally
Trial Details
NCT Number NCT07560865
Lead Sponsor Masonic Cancer Center, University of Minnesota
Collaborators: Fate Therapeutics
Conditions Astrocytoma, Glioblastoma, Progressive Disease
Enrollment 9 participants
Start Date 2026-04-23
Primary Completion 2028-06-01 (estimated)
Study Completion 2029-06-01 (estimated)
Updated on ClinicalTrials.gov 2026-05-01