Barrier Functions oF Skin in ICU: SKIN-BAR

This study aims to investigate skin barrier function in intensive care unit (ICU) patients using biosensor-based measurements. Biophysical parameters including transepidermal water loss (TEWL), skin pH, stratum corneum hydration, local skin temperature, and sebum will be assessed in anatomical regions at risk for pressure injuries. The study will examine temporal changes in these parameters, their interrelationships, and their association with pressure injury development.

NCT Number	NCT07560683
Lead Sponsor	Koç University Collaborators: Koc University Hospital
Conditions	Pressure Injuries, Skin Failure, Skin Abnormalities, Biophysical Parameters of Skin
Enrollment	156 participants
Start Date	2026-07-01
Primary Completion	2028-07-01 (estimated)
Study Completion	2028-10-01 (estimated)
Updated on ClinicalTrials.gov	2026-05-01