Weight Loss and Endocrine Disrupting Chemicals (EDCs): Lifestyle Interventions to Lose Weight and Reduce EDC Exposure in Individuals With Overweight/Obesity

Study acronym: LiveWell
StatusActive, Not Recruiting
PhaseNot applicable
Started

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Trial flagged as At Risk
Primary completion moved at least 2 months later Aug 2026 → Nov 2026
Primary endpoint added 2 → 3 primary endpoints
See other at-risk trials from Million Marker Wellness, Inc.

Record History

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  1. Primary completion pushed from Aug 2026 to Nov 2026 Show 4 more changesShow less
    • Study completion pushed from Sep 2026 to Nov 2026
    • Eligibility criteria expanded, about 12 words
    • Secondary endpoints: details revised at 1 of 2 entries
    • Publications: details revised at 56 of 56 entries
  2. Primary endpoint(s) modified
    • Secondary endpoints: 3 to 2
    v4
  3. Collaborators: 1 to 2v3
  4. Study description expanded, about 2 wordsv2
  5. Study First Submitted
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The goal of this study is to examine the relationship in individuals with overweight/obesity and endocrine disrupting chemical (EDC) exposure through a two-armed, randomized clinical trial. The main questions this study aims to answer are: 1. If MM's 12-week EDC intervention program (EDC testing and report-back, EDC reduction curriculum) can reduce weight? 2. If a 12-week validated digital weight loss program can reduce EDC exposures? 3. What is the effectiveness of the two interventions at reducing weight and urinary EDC metabolites? Participants will be assigned to one of these two arms. Participants will collect their urine and blood samples pre- and post-intervention, and will take a comprehensive exposure survey before sending back their samples. This exposure survey will ask about participant's weight loss literacy, environmental health literacy, product use, diet, and lifestyle behaviors.
Trial Details
NCT Number NCT07560579
Lead Sponsor Million Marker Wellness, Inc.
Collaborators: National Institute of Environmental Health Sciences (NIEHS), Mayo Clinic
Conditions
(from sponsor)		 Obesity & Overweight, Environmental Exposure, Overweight (BMI > 25)
Related terms Obesity, Overweight, Weight Loss
Enrollment 226 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov