Clinical Outcomes and Patient Satisfaction With Velnez Versus Nasopore in Nasal Surgery

This clinical trial evaluated two absorbable nasal packing materials - VELNEZ and NASOPORE - in adult patients (18-70 years) who underwent nasal surgery, including septoplasty, FESS, or turbinoplasty. The study addressed two core questions: whether VELNEZ offered superior haemorrhage control and faster biodegradation, and whether it reduced postoperative pain, fibrosis, adhesion, and discomfort compared to NASOPORE. Participants were randomised to receive either packing material following surgery. They were monitored on the day of surgery for haemostasis and device performance, then followed up with clinical and endoscopic assessments - including pain scoring and adverse event tracking - through Day 90.

NCT Number	NCT07560254
Lead Sponsor	Ayu, Inc.
Conditions	Rhinosinusitis, Sinusitis, Chronic Rhino-sinusitis
Enrollment	20 participants
Start Date	2024-09-11
Primary Completion	2025-04-11 (estimated)
Study Completion	2025-07-20 (estimated)
Updated on ClinicalTrials.gov	2026-05-06