Triple-Modal Therapy in Early-Stage Femoral Head Osteonecrosis (TM-ONFH)

This retrospective observational study evaluates the clinical and radiological outcomes of patients with early-stage osteonecrosis of the femoral head treated with a combination of core decompression, stromal vascular fraction (SVF), and hyperbaric oxygen therapy (HBOT). A total of 24 patients were included and followed for two years. The aim of this study is to assess the effectiveness of this combined therapeutic approach in improving clinical outcomes and preventing disease progression.

NCT Number	NCT07560163
Lead Sponsor	Ankara City Hospital Bilkent
Conditions	Osteonecrosis of the Femoral Head
Enrollment	24 participants
Start Date	2025-01-22
Primary Completion	2025-09-22 (estimated)
Study Completion	2025-11-22 (estimated)
Updated on ClinicalTrials.gov	2026-05-06