Ablation With Systemic Therapy vs Liver Resection With Systemic Therapy for Colorectal Liver Metastasis

For patients with colorectal liver metastases (CRLM) ≤5 cm, Clinical guidelines recommend surgery, but a growing number of studies have shown that thermal ablation is as effective as surgery. However, the optimal treatment strategy remains unclear.This study aimed to compare outcomes between patients who underwent ablation with systemic therapy or liver resection with systemic therapy for CRLM less than 5 cm in diameter.

NCT Number	NCT07559851
Lead Sponsor	The First Hospital of Jilin University
Conditions	Colorectal Liver Metastasis (CRLM)
Enrollment	151 participants
Start Date	2018-01-01
Primary Completion	2025-03-01 (estimated)
Study Completion	2025-03-01 (estimated)
Updated on ClinicalTrials.gov	2026-04-30