Rectal Arterial Embolization vs Band Ligation for the Treatment of Internal hemOrrhoidS

The purpose of this clinical trial is to compare two standard of care non-surgical treatments for hemorrhoidal bleeding: hemorrhoidal artery embolization (HAE) versus rubber band ligation (RBL). Directly comparing these two methods may help to clarify which treatment is better for controlling hemorrhoidal bleeding, reducing symptoms, and improving patients' quality of life. HAE is a standard minimally invasive procedure to put tiny particles or coils into the blood vessel that feeds a hemorrhoid to block the blood flow (embolization). This involves using a catheter inserted into an artery, using twilight (conscious) sedation. RBL is a standard procedure that involves using small rubber bands around the base of the hemorrhoids to cut off blood flow, causing it to shrink or shrivel.

NCT Number	NCT07559630
Lead Sponsor	Jessica K. Stewart, MD Collaborators: Terumo Medical Corporation
Conditions	Hemorrhoidal Bleeding, Hemorrhoids, Internal, HAE, RBL
Enrollment	40 participants
Start Date	2026-05-19
Primary Completion	2030-11 (estimated)
Study Completion	2031-11 (estimated)
Updated on ClinicalTrials.gov	2026-07-10