Reframing Endometrial Physiology by Advanced Integrated Research

Heavy menstrual bleeding (HMB) affects 1 in 3 women and can significantly impact quality of life. Despite its prevalence, there is no accessible and accurate diagnostic test. This research will use wearable sensors, magnetic resonance imaging (MRI) scans, and biological sample collection to identify changes in the uterus linked with HMB. The investigators aim to recruit approximately 130 participants across two study sites over three years, including people with and without HMB.

NCT Number	NCT07557992
Lead Sponsor	University Hospital Southampton NHS Foundation Trust Collaborators: University of Auckland, New Zealand
Conditions	Menorrhagia Due to Benign Causes
Enrollment	100 participants
Start Date	2026-02-06
Primary Completion	2029-02-01 (estimated)
Study Completion	2030-02-01 (estimated)
Updated on ClinicalTrials.gov	2026-04-30